Efficacy and safety of trastuzumab deruxtecan therapy

Antibody-drug conjugates (ADCs) are a new generation of drugs that currently represent one of the most effective treatment options for cancer.ADCs target a specific target (antigen) that is selectively expressed on a tumour cell.Binding of ADCs to a tumour cell results in targeted intracellular delivery of cytotoxic drugs which causes cell death.An

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An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer

Armin Mooranian,1 Rebecca Negrulj,1 Nigel Chen-Tan,2 Gerald F Watts,3 Frank Arfuso,4 Hani Al-Salami11Biotechnology and Drug Development Research Laboratory, School Circle Wood Sign of Pharmacy, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, 2Faculty of Science and Engineering, Curtin University, 3Scho

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The atmospheric background situation in northern Scandinavia during January/February 2003 in the context of the MaCWAVE campaign

The atmosphere background wind field controls the propagation of gravity waves from the troposphere through the stratosphere into the mesosphere.During January 2003 the MaCWAVE campaign took place at Esrange, with the purpose of observing vertically ascending waves induced by orography.Temperature data from the U. Bonn lidar at Esrange (68°

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