Antibody-drug conjugates (ADCs) are a new generation of drugs that currently represent one of the most effective treatment options for cancer.ADCs target a specific target (antigen) that is selectively expressed on a tumour cell.Binding of ADCs to a tumour cell results in targeted intracellular delivery of cytotoxic drugs which causes cell death.An
Learning Post-Stroke Gait Training Strategies by Modeling Patient-Therapist Interaction
For safe and effective robot-aided gait training, it is essential to incorporate the knowledge and expertise of physical therapists.Toward this goal, we directly learn from physical therapists’ demonstrations of manual gait assistance in stroke rehabilitation.Lower-limb kinematics of patients and assistive force applied by therapists to the
Determination of Indoor Radon Concentration in Thi Qar Province Houses by using CR-39 SSNTD
The possible detrimental health effects of the inhaled radon and its decay products are in the limelight of interest of professionals as well as of the public.In the present work the passive integrated dosimeter technique with solid state nuclear track detectors (SSNTDs) super grade CR-39, was used to measure the concentration of the radioactive ra
An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer
Armin Mooranian,1 Rebecca Negrulj,1 Nigel Chen-Tan,2 Gerald F Watts,3 Frank Arfuso,4 Hani Al-Salami11Biotechnology and Drug Development Research Laboratory, School Circle Wood Sign of Pharmacy, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, 2Faculty of Science and Engineering, Curtin University, 3Scho
The atmospheric background situation in northern Scandinavia during January/February 2003 in the context of the MaCWAVE campaign
The atmosphere background wind field controls the propagation of gravity waves from the troposphere through the stratosphere into the mesosphere.During January 2003 the MaCWAVE campaign took place at Esrange, with the purpose of observing vertically ascending waves induced by orography.Temperature data from the U. Bonn lidar at Esrange (68°